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Remember Me ( Log Out /  Change ), You are commenting using your Google account. Visit Us Now! Beilstein/REAXYS Number: 2060675 . Streptozocin (STZ) shows higher cytotoxic effect in vitro on hematological cell lines compared to Alloxan (ALX). 142 Streptozotocin has unique activities for nitrosoureas, including inducing diabetes in animals 143,144 and a lack of any significant bone marrow toxicity.